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The Harm of PKD

  The Harm of PKD

  In addition to the kidneys, ADPKD affect multiple organs and tissues. About 1/3 patients can have a liver cyst, the number of cysts increased with the increasing in age, the clinical manifestations include liver pain, discomfort and early sense of fullness and so on.

  Cysts can also occur in the pancreas, spleen, esophagus, thyroid gland, endometrial, seminal vesicle and epididymis and so on. These isolated cysts can not cause clinical symptoms. Heart valve abnormalities, cardiac hypertrophy and congenital heart disease is another common renal manifestations of ADPKD.

  83% end-stage ADPKD patients confirmed by barium enema colonic diverticulum. Aneurysms can occur in cerebral artery, abdominal aorta, thoracic aorta, atrial septal and coronary artery, cystic or fusiform. Intracranial aneurysms are the most common, and the incidence of ADPKD is about 12%.

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