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Elderly nephrotic syndrome

  Nephrotic syndrome (nephrotic syndrome) is a large number of proteinuria (≥ 3.5g / d), hypoproteinemia (≤ 30g / d), hyperlipidemia and edema as the main features of glomerular lesions. Is a common manifestation of glomerular disease. Senile nephrotic syndrome, clinically divided into two categories, one is the primary nephrotic syndrome, is the primary manifestation of primary glomerular disease; the second category is caused by systemic diseases, said For secondary nephrotic syndrome.

  The disease often in the infection (tonsillitis, pharyngitis or general upper respiratory tract infection), or cold, tired onset, onset can be anxious to slow, sometimes onset insidious, the main performance:

  1. edema was systemic, physical, concave edema. Early more common in the ankle, morning eyelid, facial edema, with the course of development, edema to the body and chest, abdominal and scrotal effusion, or even pericardial effusion. Elderly patients with severe edema can occur when the heart failure.

  2. A large number of protein peanut protein> 3.5g / 24h, severe cases of more than ten grams, was selective or non-selective proteinuria.

  3. Hypoproteinemia plasma total protein decreased, mainly plasma albumin decreased. Mostly in the 10 ~ 30g / L (1 ~ 3g / dl), occasionally reduced to 5.8g / L (0.58g / dl).

  4. Most patients with hyperlipidemia blood cholesterol, phospholipids and triglyceride can be increased. These 4 points, a large number of proteinuria and hypoproteinemia as a prerequisite for diagnosis.


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