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Pediatric congenital nephrotic syndrome

  Congenital nephrotic syndrome refers to the onset of nephrotic syndrome within 3 months after birth. It has the same clinical manifestations of childhood nephrotic syndrome, that is, at birth or within 3 months after birth, a large number of proteinuria, high edema, hyperlipidemia and hypoproteinemia. But its etiology, pathological changes, prognosis and older children or adults are different.

  According to the cause of classification, usually divided into two categories:

  1. Primary include Finnish congenital nephrotic syndrome, diffuse mesangial sclerosis, minimal lesions, focal segmental sclerosis.

  2. secondary can be secondary to infection (congenital syphilis, congenital poisonous protozoa disease, congenital giant cell inclusion body disease, rubella, hepatitis, malaria, AIDS, etc.), mercury poisoning, infant systemic lupus erythematosus, hemolysis Uremic syndrome, a patellar syndrome, Drash syndrome, renal vein thrombosis and so on.


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