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Diagnosing Lupus Nephritis Diagnosed

  Diagnosing Lupus Nephritis Diagnosed


One of the first signs of lupus nephritis is blood in your urine or extremely foamy urine. High blood pressure and swelling in your feet also might indicate lupus nephritis. Tests that will help your doctor make a diagnosis include the following:


  Blood Tests

  Your doctor will look for elevated levels of waste products, such as creatinine and urea. Normally, the kidneys filter out these products.

  24-Hour Urine Collection

  This test measures the kidney’s ability selectively to filter wastes. It determines how much protein appears in urine over 24 hours.

  Urine Tests

  Urine tests measure kidney function. They identify levels of:


  red blood cells

  white blood cells

  Iothalamate Clearance Testing

  This test uses a contrast dye to see if your kidneys are filtering properly.

  Radioactive iothalamate is injected into your blood. Your doctor will then test how quickly it’s excreted in your urine. They may also directly test how quickly it leaves your blood. This is considered to be the most accurate test of kidney filtration speed.

  Kidney Biopsy

  Biopsies are the most accurate and also most invasive way to diagnose kidney disease. Your doctor will insert a long needle through your stomach and into your kidney. They’ll take a sample of kidney tissue to be analyzed for signs of damage.


  Ultrasounds use sound waves to create a detailed image of the kidney. Your doctor will look for anything abnormal in the size and shape of your kidney.


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